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2c, Extended Data Fig
Introduction# Melanotan-2 and PT-141 share a direct lineage: PT-141 (bremelanotide) was developed from Melanotan-2 when researchers at the University of Arizona noticed that their tanning peptide had unexpected pro-sexual effects
Estrogen therapy has been associated with improved insulin sensitivity, reduced central fat distribution, and enhanced quality of life (Santen et al., Menopause, 2020)
Improved Heart Health Markers Excess body weight can add stress to the cardiovascular system
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Reduced glutathione levels can lead to increased oxidative stress and impaired detoxification, while decreased methylation can lead to a range of health issues, including mood disorders, cognitive dysfunction, and cancer
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